ER takes a faster track
نویسندگان
چکیده
منابع مشابه
ER takes a faster track
Suicide attempt linked to breakdown he Golgi apparatus breaks down temporarily to segregate into daughter cells during mitosis, but during apoptosis the organelle fragments irreversibly. On page 637, Chiu et al. report that cleavage of a critical tethering protein during apoptosis not only drives the fragmentation of the Golgi apparatus, but also appears to help propagate the apoptotic signal. ...
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control may kick in even before a kinetochore is assembled. The mitotic checkpoint— controlled by Mad1, Mad2, Bub1, BubR1, and Bub3— delays anaphase by inhibiting APC until all kinetochores are properly attached to the spindle. Because inhibition of Mad2 leads to an accelerated mitosis and a precocious anaphase, it has been assumed that the checkpoint itself also regulates mitotic timing. But M...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2002
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1594iti3